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GLR Stick Setria® Orosoluble 30 sticks YAMAMOTO

€ 30,51 € 35,90

Deliver between December 20 and December 23
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Yamamoto® Research GLR Stick Setria® Orosolubile is a food supplement in orosoluble stick form that provides 250 mg per daily dose of Reduced L-Glutathione (Setria®) . Glutathione is a powerful molecule with a antioxidant who participates on the front line in the defense of the body from oxidative stress and from the action of free radicals and which is capable of protect hepatocytes from toxic molecules which could cause liver damage. The formulation in practice orodispersible stick ensures rapid dissolving sublingual absorption This allows the body to rapidly and optimally absorb glutathione from the sublingual venous circulation, which is a tributary of the superior vena cava, bypassing the intestinal activity of gamma-glutamyltransferase and avoiding enterocyte metabolic avidity. This bypasses the " hepatic filter " and avoids the first-pass metabolism that normally occurs in the liver, which deactivates a large portion of the glutathione molecule, making it less functional and effective.

Glutathione is one of our first lines of defense, a ubiquitous molecule, meaning it is present throughout our organism, but it is It is particularly concentrated in the liver , where it protects liver cells from toxic molecules: in this case, glutathione "binds" to toxic metabolites, neutralizing them. Reduced glutathione is in fact able to give up its hydrogen (H+), which acts as an acceptor of an electron (e-) coming from reactive oxygen molecules, or free radicals. At this point, having eliminated the danger caused by free radicals, glutathione can regain its antioxidant activity and return to its reduced form. Glutathione's ability to to continually regenerate is the reason why this molecule is considered The most powerful antioxidant in the human body . Glutathione's biological functions support its clinical utility in various situations, first and foremost its ability to protect the liver from the action of toxic substances.

Forever oral intake of glutathione was the limiting factor for its use in dietary supplements: the human intestine contains significant quantities of the gamma-glutamyltranspeptidase enzyme, responsible for the degradation of glutathione after oral ingestion. This molecule was therefore truly effective only when administered by injection. Thanks to the special absorption of GLR Stick Setria® Orosolubile, a new generation reduced glutathione supplement in practical orodispersible stick , it is possible to skip the enzymatic steps responsible for the loss of efficacy of the molecule, guaranteeing the body optimal bioavailability of Glutathione.

Why is the action of glutathione so important?

Twenty-four hours a day, seven days a week, free radicals are busy attacking our bodies at the cellular level. Scientists have discovered that this constant attack impacts overall health and well-being, including the health of our tissues and their aging. It appears that combating the damage caused by free radicals can allow us to age more gracefully and live a healthier life. For this reason, it's important to ensure our bodies have optimal levels of glutathione, a molecule that effectively combats oxidative stress.

How can GLR Stick Setria® Orosolubile help your body fight free radicals?

Eating, exercising, and even breathing can create free radicals. These molecules, once formed, attack the body at the cellular level, stealing electrons from other molecules and triggering a chain reaction. GLR Stick provides the body with reduced glutathione, a molecule that binds to free radicals, neutralizing their action.

Why is glutathione called the “ Master antioxidant ” or “ King of antioxidants ”?

Glutathione not only neutralizes free radicals: it also has the ability to reactivate other antioxidant molecules, such as vitamins C and E. Normally, in fact, after antioxidants (such as vitamin C and vitamin E) have done their job by inactivating free radicals, they themselves become unstable radicals. Glutathione helps to recycle these molecules, bringing them back into function and extending their ability to attack free radicals: for this reason Glutathione is considered the “ master ” or “ King ” molecule of all the antioxidants in the body.

How does GLR Stick Setria® Orosolubile help eliminate toxins?

Glutathione supports the function of the liver, kidneys, gastrointestinal tract and intestines, the main detoxification paths of the body.

It acts on two different fronts:

  1. Helps eliminate toxins, ingested chemicals and potential carcinogens that the body has already absorbed;

  2. It intercepts and neutralizes toxins in the gastrointestinal tract before they are absorbed.

Why can GLR Stick Setria® Orosolubile also be useful for athletes?

Scientific research seems to suggest that Setria® Glutathione may support Nitric Oxide (NO) production when combined with L-Citrulline and when used in endurance performance.

**Setria® also appears to help maintain elevated NO levels, which may reduce fatigue and speed recovery.

GLR Setria® Sublingual can therefore provide an aid for strength training, maintaining the increase in nitric oxide production post-workout.

** Patent Pending

Nutritional Information
30 stick
blood orange
Nutritional information
Per daily dose (1 stick = 1.0 g)
L-glutathione (Setria®)
250 mg

How to use and take
Directions for use: take 1 orodispersible stick per day.
Our advice

We recommend taking GLR Stick Setria Orosolubile as part of your morning routine. It's important to take glutathione after the recovery processes that normally occur in the body during the night, because endogenous glutathione levels are naturally lower in the morning upon awakening. We don't recommend taking GLR Stick Setria Orosolubile immediately after a workout, because during this phase, despite high free radical production, the body undergoes physiological adaptations that must not be disrupted. It's always best to take antioxidant molecules away from workouts.

Frequently asked questions

What is the role of glutathione in liver detoxification?

Glutathione plays a key role in liver detoxification, as it is involved in numerous processes that eliminate toxic substances from the body. The liver is the primary organ involved in detoxifying chemicals and drugs in the body: these compounds are metabolized through a series of enzymatic reactions that make them more water-soluble and therefore easily eliminated through urine or feces.

Glutathione is a essential cofactor for two important enzymes involved in this detoxification process : the glutathione S-transferase (GST) and the Glutathione peroxidase (GPx) . GST is involved in the conjugation of toxic substances with glutathione, which increases their solubility and promotes their elimination from the body. GPx, on the other hand, is an antioxidant enzyme that uses glutathione to neutralize free radicals and other oxidants that can damage liver cells. Additionally, glutathione plays an important role in regulating the liver's redox balance. protecting liver cells from oxidative damage caused by reactive oxygen species (ROS) produced during the detoxification process. These ROS can damage cellular DNA, proteins, and lipids, leading to inflammation and cell damage.

How can glutathione help prevent cellular aging?

Glutathione may help prevent cellular aging through its antioxidant action and its capacity to protect cells from damage caused by free radicals . Furthermore, it is involved in numerous cellular processes that contribute to the Prevention of cellular aging , such as cell cycle regulation, DNA protection from mutations, and promoting the repair of damaged DNA. However, glutathione levels in the body tend to decline with age, making cells more vulnerable to oxidative damage and contributing to cellular aging. Therefore, maintaining adequate glutathione levels in the body is important to prevent or slow down cellular aging.

What are the consequences of a glutathione deficiency in the body?

A glutathione deficiency can have several negative consequences for the body's health and well-being, compromising immune system function, increasing oxidative stress, causing liver damage, reducing DNA repair capacity, and increasing sensitivity to drugs and toxins. Therefore, maintaining adequate glutathione levels in the body through a balanced diet, regular exercise, and the use of nutritional supplements, if necessary, can be helpful in preventing or reducing the risk of these negative consequences.

Why choose our supplement:

  • Extremely powerful molecule with antioxidant action, considered the “Master of Antioxidants” of the entire human organism;
  • Convenient stick format, practical and functional;
  • Improved absorption and bioavailability thanks to sublingual administration;
  • It counteracts the negative action of free radicals and helps eliminate toxins;
  • Supports liver and gastrointestinal function;
  • 250mg Setria® quality reduced L-Glutathione per stick;
  • It supports the regeneration and reactivation of other antioxidants, such as vitamins C and E;
  • Ingredients of the highest quality and safety;
  • 100% Italian production.
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